Propylthiouracil induced ANCA positive vasculitis. A case report

Authors

  • Marco Antonio Soto Fonseca Hospital Escuela Universitario, Universidad Nacional Autónoma de Honduras. Tegucigalpa, Honduras.
  • Katherine Fernanda Medina Ramírez Universidad Nacional Autónoma de Honduras. Tegucigalpa, Honduras.
  • Karen Sánchez Barjún Universidad Nacional Autónoma de Honduras. Tegucigalpa, Honduras

DOI:

https://doi.org/10.20453/rmh.v32i2.3983

Abstract

ANCA vasculitis associated to propylthiouracil (PTU) is a rare condition with an incidence of 0.47-0.71 cases per 100,000 patients. It affects mainly minor caliber blood vessels. The skin, kidneys and lungs are the organs most affected. To make the diagnosis it is necessary to have a high index of suspicion and rely on histopathologic findings of skin lesions plus a positive ANCA test. Stopping the inducing drug is usually necessary to manage this condition. We report the case of a 45-year-old woman who consumed PTU for two years for the treatment of hyperthyroidism presenting with painful purpuric plaques in the lower limbs.

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Published

2021-07-19

How to Cite

1.
Soto Fonseca MA, Medina Ramírez KF, Sánchez Barjún K. Propylthiouracil induced ANCA positive vasculitis. A case report. Rev Méd Hered [Internet]. 2021 Jul. 19 [cited 2025 Feb. 3];32(2):103-7. Available from: http://44.198.254.164/index.php/RMH/article/view/3983

Issue

Vol. 32 No. 2 (2021): April-June

Section

CASE REPORTS

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