Analysis of vaccination against SARS-CoV-2 and mortality due to COVID-19 in the Callao region, Peru during the period 2021-2022
DOI:
https://doi.org/10.20453/rmh.v36i2.5651Palavras-chave:
COVID-19, mortality, vaccination, pandemicResumo
Objective: To determine the relationship between SARS-CoV-2 vaccination dimensions and COVID-19 death rates in the Callao region. Methods: A cross-sectional study based on the Ministry of Health databases was carried out. A total of 44,867 records from the Callao region were analyzed for the period 2021 to 2022. To assess the association of interest, logistic regression models were constructed, reporting crude odds ratios (cOR) and adjusted odds ratios (aOR). Results: The logistic regression models showed that vaccination had a protective effect against death from COVID-19, with an aOR of 0.19 (p<0.001) after controlling for sex, age, hospitalization, ICU admission, and pandemic wave, compared to the reference group (unvaccinated). Conclusions: Vaccination provides a monotonic protective effect against death from COVID-19 in the Región Callao.
Downloads
Referências
(CSSE) CfSSaE. COVID-19 Dashboard. 2023. Disponible en: https://coronavirus.jhu.edu/map.html
Cho M, Levin R. Implementación del plan de acción de recursos humanos en salud y la respuesta a la pandemia por la COVID-19. Rev Panam Salud Públ 2023; 46, e52. doi: 10.26633/RPSP.2022.52
Ministerio de Salud. Vacuna COVID-19 en el Perú [Internet]. 2023. Disponible en: https://www.minsa.gob.pe/reunis/data/vacunas-covid19.asp
Dirección Regional de Salud del Callao. Análisis de Situación de Salud. Callao: DIRESA Callao; 2021.
Sadoff J, Gray G, Vandebosch A, Cárdenas V, Shukarev G, Grinsztejn B, et al: Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19. N Engl J Med 2021, 384(23):2187-2201. doi: 10.1056/NEJMoa2101544
World Health Organization. Coronavirus disease (COVID-19) [Internet]. 2020. Disponible en: https://www.who.int/health-topics/coronavirus#tab=tab_1
Nordström P, Ballin M, Nordström A. Risk of infection, hospitalization, and death up to 9 months after a second dose of COVID-19 vaccine: a retrospective, total population cohort study in Sweden. Lancet. 2022;399(10327):814-23. doi: 10.1016/S0140-6736(22)00089-7
Valladares-Garrido MJ, Zeña-Ñañez S, Peralta CI, Puicón-Suárez JB, Díaz-Vélez C, Failoc-Rojas VE. COVID-19 Vaccine Effectiveness at a Referral Hospital in Northern Peru: A Retrospective Cohort Study. Vaccines (Basel). 2022;10(5): 812. doi: 10.3390/vaccines10050812
Silva-Valencia J, Soto-Becerra P, Escobar-Agreda S, Fernandez-Navarro M, Elorreaga OA, Mayta-Tristán P, et al. Relative vaccine effectiveness of the booster dose of COVID-19 vaccine for preventing death in individuals with a primary regimen based on the BBIBP-CorV, ChAdOx1-S, or BNT162b2 vaccines during the Omicron wave in Peru: A nested case-control study using national population data. Vaccine. 2022; 40(45):6512-6519. doi: 10.1016/j.vaccine.2022.09.066
Fano-Sizgorich D, Vásquez-Velásquez C, Orellana LR, Ponce-Torres C, Gamboa-Serpa H, Alvarez-Huambachano K, et al. Risk of death, hospitalization and intensive care unit admission by SARS-CoV-2 variants in Peru: a retrospective study. Int J Infect Dis. 2023; 127:144-9. doi: 10.1016/j.ijid.2022.12.020
Nah EH, Cho S, Park H, Kim S, Noh D, Kwon E, et al. SARS-CoV-2 Antibody Response and Sustainability after a Third Dose of BNT162b2 in Healthcare Workers at Health Promotion Centers. Viruses. 2023; 15(3):751. doi: 10.3390/v15030751.
Urrunaga-Pastor D, Fernandez-Guzman D, Caira-Chuquineyra B, Herrera-Añazco P, Benites-Zapata VA, Bendezu-Quispe G. Prevalence and factors associated with not receiving the booster dose of the COVID-19 vaccine in adults in Latin America and the Caribbean. Travel Med Infect Dis. 2022; 50:102409. doi: 10.1016/j.tmaid.2022.102409
Bendezu-Quispe G, Caira-Chuquineyra B, Fernandez-Guzman D, Urrunaga-Pastor D, Herrera-Añazco P, Benites-Zapata VA. Factors Associated with Not Receiving a Booster Dose of COVID-19 Vaccine in Peru. Vaccines (Basel). 2022; 26;10(8):1183. doi: 10.3390/vaccines10081183
Watson OJ, Barnsley G, Toor J, Hogan AB, Winskill P, Ghani AC. Global impact of the first year of COVID-19 vaccination: a mathematical modelling study. Lancet Infect Dis. 2022;22(9):1293-302. doi: 10.1016/S1473-3099(23)00566-2.
Lazarus JV, Wyka K, White TM, Picchio CA, Gostin LO, Larson HJ, et al. A survey of COVID-19 vaccine acceptance across 23 countries in 2022. Nat Med. 2023;29(2):366-75. doi: 10.1038/s41591-022-02185-4.
Bergen N, Johns NE, Chang Blanc D, Hosseinpoor AR. Within-Country Inequality in COVID-19 Vaccination Coverage: A Scoping Review of Academic Literature. Vaccines. 2023;11(3):517. doi: 10.3390/vaccines11030517
López L, Portugal W, Huamán K, Obregón C. Efectividad de vacunas COVID-19 y riesgo de mortalidad en Perú: un estudio poblacional de cohortes pareadas. An Fac med. 2022 Abr; 83(2):87-94. doi: 10.15381/anales.v83i2.21531
Downloads
Publicado
Como Citar
Edição
Seção
Licença
Copyright (c) 2025 Cinthya Vasquez-Velasquez, Diego Fano-Sizgorich, Carol Ordoñez-Aquino, Zoila Diaz-Tavera, Gustavo F. Gonzales

Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
Os autores cedem os seus direitos à RMH para que estas possam divulgar o artigo através dos meios ao seu alcance. A revista fornecerá formulários de declaração de autoria e autorização para a publicação do artigo, que deverão ser entregues juntamente com o manuscrito. Os autores conservam o direito de partilhar, copiar, distribuir, executar e comunicar publicamente o seu artigo, ou parte dele, mencionando a publicação original na revista.