Effect of the ethanolic extract of Erythroxylum novogranatense var. truxillense and Erythroxylum coca var. coca front to Streptococcus mutans.

Authors

  • María Del Rosario Salcedo Calderón Universidad Nacional Mayor de San Marcos. Lima, Peru.
  • Hilda Moromi Nakata Department of Basic Sciences of the Faculty of Dentistry Universidad Nacional Mayor de San Marcos. Stomatological Research Institute. Lima, Peru.

DOI:

https://doi.org/10.20453/reh.v32i4.4376

Keywords:

Coca, Streptococcus mutans, Antibacterial agent

Abstract

Objectives: To compare the antibacterial effect of the ethanolic extracts of two varieties of coca leaf “in vitro”: Erythroxylum coca var. coca and Erythroxylum novogranatense var. truxillense on Streptococcus mutans. Material and methods: Using the method of diffusion by discs, the ethanolic extracts of the two varieties were applied at concentrations 100%, 50%, 25% and 12.5% with positive controls of Chlorhexidine 0.12% and negative of 96º Alcohol in the cultures of the Streptococcus mutans strain (ATCC 25175) sown in Tripticasa Soya Agar. Incubation was performed at 37 ° C for 48 hours under conditions of partial anaerobiosis. The statistical analysis was carried out with the SPSS Version 22 program by means of the Mann Whitney U Test and Kruskal Wallis. Results: Erythroxylum coca var. coca 100% and 50% had a greater inhibition halo 18.65 ± 2.434 and 17.10 ± 2.654 with respect to the ethanolic extract of Erythroxylum novogranatense var. truxillense that were 15.30 ± 1.895 and 14.05 ±1.932. respectively. Conclusions: It was determined that the ethanolic extract of Erythroxylum coca var. coca 100% and 50% has a greater antibacterial effect than the Erythroxylum novogranatense var. truxillense 100% against Streptococcus mutans.

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Published

2022-12-15

How to Cite

1.
Salcedo Calderón MDR, Moromi Nakata H. Effect of the ethanolic extract of Erythroxylum novogranatense var. truxillense and Erythroxylum coca var. coca front to Streptococcus mutans. Rev Estomatol Herediana [Internet]. 2022 Dec. 15 [cited 2024 Dec. 22];32(4):365-70. Available from: http://44.198.254.164/index.php/REH/article/view/4376