EspPulmonary and Multifocal Osseous Tuberculosis in an Immunocompetent Patient: Case Reportañol
DOI:
https://doi.org/10.20453/rmh.v35i2.5234Keywords:
Tuberculosis extrapulmonary, Immunity, Tuberculosis osteoarticular, Polymerase Chain ReactioAbstract
Extrapulmonary Tuberculosis, accounting for 14% of total tuberculosis cases, represents an uncommon manifestation, with osteoarticular involvement being a rare form. We present the case of a 28-year-old male patient who initially exhibited respiratory symptoms and subsequently developed acute pain and swelling in the second finger of the right hand after exertion. Specific treatment was initiated at a peripheral center upon the isolation of Mycobacterium tuberculosis in sputum. However, due to persistent symptoms and the need for further investigations, the patient was referred to a more specialized center. A biopsy of the swelling was performed, yielding a positive result for GeneXpert MTB/RIF. The initial anatomopathological description prompted further investigation, including a biopsy of an incidentally discovered vertebral lesion at the D9 level. Both reports concluded that the lesions were secondary to tuberculosis. In summary, a diagnosis of disseminated tuberculosis with multifocal osteoarticular involvement was established, and the patient continues the sensitive antitubercular treatment regimen.
Downloads
References
World Health Organization (WHO). Global tuberculosis report. 2023. Disponible en: https://iris.who.int/bitstream/handle/10665/373828/9789240083851-eng.pdf?sequence=1
Purohit M, Mustafa T. Laboratory diagnosis of extrapulmonary tuberculosis (EPTB) in resource- constrained setting: state of the art, challenges and the need. J Clin Diagn Res. 2015; 9:EE01eEE06.
Kulchavenya E. Extrapulmonary tuberculosis: are statistical reports accurate? Ther Adv Infect Dis. 2014; 2(2):61–70. doi: 10.1177/2049936114528173.
Villena-Suarez JR, Vicente W, Taxa L, Cuéllar L, Nuñez-Butrón MT, Villegas V et al. Tuberculosis que imita cáncer: casos derivados al Instituto Nacional de Enfermedades Neoplásicas, Lima-Perú. Rev perú med exp salud publica. 2018; 35(1):77-83. doi:10.17843/rpmesp.2018.351.3602.
Análisis Situacional de la Tuberculosis Región Callao; 2021. Disponible en: https://www.diresacallao.gob.pe/wdiresa/documentos/boletin/epidemiologia/asis/FILE0006702016.pdf
Ministerio de Salud. NTS Nº200-MINSA/DGIESP-2023. Norma Técnica de Salud para el Cuidado Integral de la Persona afectada por Tuberculosis, Familia y Comunidad. Lima. MINSA. 2023. Disponible en: https://bvs.minsa.gob.pe/local/fi-admin/RM-339-2023-MINSA.pdf
Dong J, Wang H. Multisystemic tuberculosis presenting with pulmonary, pleura, intestinal and bone involvement. Am J Med Sci. 2022; 364(5):e4-e5. Doi:10.1016/j.amjms.2022.05.024
Adhikari S, Basnyat B. Extrapulmonary tuberculosis: a debilitating and often neglected public health problem. BMJ Case Rep. 2018; 11(1):e226098. Doi:10.1136/bcr-2018-226098
Lynn MM, Kukanesen JR, Khan AW. Troublesome Tuberculosis: A Case Report on Multi-focal Tuberculous Osteomyelitis in An Immunocompetent Patient. J Clin Med Res. 2012; 4(1):73-6. Doi:10.4021/jocmr758e
Chaudhry LA, Eissa EB, Chaudhry S. A 35-year-old immuno-competent male with open pulmonary tuberculosis associated with extra-ordinary extensive extra-pulmonary tuberculosis. Int J Mycobacteriol. 2013; 2(3):183-6. Doi:10.1016/j.ijmyco.2013.05.005
Sharma BK, Singh VK, Nishant K, Das D. Scapular bone destruction: do not forget to think of tuberculosis in endemic areas. BMJ Case Rep. 2013; 2013:bcr2013200051. Doi:10.1136/bcr-2013-200051
Singh J, Dinkar A. Positive outcome of pulmonary tuberculosis associated with extraordinary extensive extrapulmonary tuberculosis in an immunocompetent adult. Int J Mycobacteriol. 2018; 7(2):183-185. Doi:10.4103/ijmy.ijmy_61_18
Yu Y, Kong Y, Ye J, Wang A. Performance of conventional histopathology and GeneXpert MTB/RIF in the diagnosis of spinal tuberculosis from bone specimens: A prospective clinical study. Clin Biochem. 2020; 85:33-37. Doi: 10.1016/j.clinbiochem.2020.08.010
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Ramon Rolando Cámara-Reyes, RRCR, Marco Antonio Zuñiga-Rosas, MAZR
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors assign their rights to the RMH so that may disseminate the article through the means at their disposal. The journal will provide forms of affidavit of authorship and authorization for the publication of the article, which shall be submitted with the manuscript. Authors retain the right to share, copy, distribute, perform and publicly communicate their article, or part of it, mentioning the original publication in the journal.