Use of biopsy and polymerase chain reaction for the diagnosis of cerebral toxoplasmosis in an HIV-positive female patient. A case report
DOI:
https://doi.org/10.20453/rmh.v35i4.5670Keywords:
Toxoplasmosis Cerebral, Biopsy, Polymerase Chain Reaction, Pregnancy, AIDS-Related Opportunistic InfectionsAbstract
Infection by T. gondii is a significant cause of morbidity and mortality among people infected with HIV. The disease presents cerebral or encephalic involvement, especially among severely immunosuppressed patients. We present the case of HIV-infected pregnant women who presented with focal neurological manifestations during the second trimester of gestation. A single intracerebral lesion was found on brain imaging, and a brain biopsy and PCR identified toxoplasmosis. She improved clinically and radiographically after receiving proper treatment. The main contribution of our case is implementing a molecular test to define the diagnosis instead of a therapeutic challenge that may not make the diagnosis.
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Copyright (c) 2024 Ramon Rolando Cámara-Reyes, Marco Antonio Zuñiga-Rosas, Eddie Giampiere Díaz-Carrión
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